NIOSH-listed hazardous drugs require more than a standard compounding bench. USP Chapter 800 defines how pharmacies contain, handle, and clean up HD compounds to protect staff, patients, and the environment. TFC operates a dedicated HD containment suite for qualifying prescriptions.
USP <800> applies to drugs on the NIOSH List of Hazardous Drugs — including many hormones, certain antineoplastics, and other agents with documented occupational exposure risks. The chapter sits alongside USP <795> (non-sterile) and USP <797> (sterile): HD work must follow <800> containment whether the final preparation is a cream, capsule, or injection.
For prescribers, the practical question is not whether a pharmacy “does compounding” but whether it has the facility, training, and documentation to handle your HD compound safely. For facility administrators, the same capability supports LTC residents who receive HD preparations prepared to order.
Read our prescriber guide on sterile standards: What we mean when we say USP <797>.
Dedicated hazardous-drug compounding area with engineering controls designed to prevent cross-contamination into non-HD spaces.
CSTDs and HD-specific handling protocols for receiving, manipulating, and dispensing NIOSH-listed ingredients.
Routine residue testing on high-touch surfaces in the HD suite, with documented action limits and remediation procedures.
Documented HD garbing, spill response, and waste segregation training for staff who enter the containment area.
Compounding operations reviewed under Pharmacy Compounding Accreditation Board standards, including HD handling policies.
Independent potency and stability testing through Eagle Analytical when a prescription or facility contract requires documented verification.
Prescriber-directed HD preparations — including hormone therapy and oncology-supportive dosage forms — compounded under USP <795>, <797>, and <800> as applicable. See our BHRT page and compounding hub.
ACHC LTC-accredited services for SNFs, ALFs, group homes, and hospice partners who need HD preparations in bubble-pack or unit-dose workflows. See For Facilities and Long-Term Care.
Call the compounding desk at (323) 348-4205, fax (323) 348-4213, or visit For Prescribers.